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Disease Burden

Leading Institutes

This research priority area aims to develop and shape an overarching strategy to tackle future pandemics.

Our goal: lessen health and social impacts on individuals, while also keeping costs manageable for society.

The “Disease Burden” focal area investigates the current population immunity levels—particularly to respiratory pathogens— by exploring past infections and vaccinations. We’re also uncovering how immune disorders, both congenital and acquired, shape disease progression and what drives severe cases. With these insights, we’re crafting both medical and non-medical solution that will improve individual health during future pandemics.

Our mission? To build powerful strategies that protect everyone.

Mental health is a vital part of individual health. That’s why we focus heavily on what people need to stay mentally strong during a pandemic—especially children and young adults. Our goal is to understand and support the building blocks of mental health and resilience in the next generation.

Science communication and outreach also play a key role in this focal area. Building trust in science begins with sharing clear, easily comprehensible messages. Only when people truly receive—not just hear— these messages, can we effectively combat misinformation and encourage greater acceptance of protective measures.

Our working packages

03

Determining pre-pandemic immunity and vulnerability in the population (DRFZ, LIV)

04

Investigating how pathogens cause disease and evaluating pharmaceutical and non-pharmaceutical interventions to reduce their impact in animal models (HKI, LIV)

05

Identifying medical and socioeconomic vulnerability factors that contribute to chronic disease burden (LIV, FZB)

06

Determining factors that make people vulnerable to psychological stress and promoting protective factors that enhance resilience (IWM, DIE)

07

Boosting adherence to infection control measures through better science communication (IWM, DIE)

Participating Institutes

Transdisciplinary Activities

Call for an European Influenza Research and Response Network

Respiratory viruses, such as influenza viruses, have high pandemic potential. We recommend establishing a European influenza research network to gather insights for prevention.

Interview: Why We Are Not Prepared for the Next Pandemic

Prof. Dr. Gülsah Gabriel in an interview with the Frankfurter Allgemeine Zeitung on pandemic preparedness.

Interview: How Dangerous Is the Current Flu Wave?

Prof. Dr. Gülsah Gabriel in the podcast Tonspur Wissen on the dangers of influenza.

Interview: Sex-Specific Personalised Medicine

Prof. Dr. Gülsah Gabriel in an interview with the Volkswagen Foundation on drugs that influence hormone metabolism and could help prevent severe viral disease progression in the future.

Interview: Is This Flu Wave Unusual, Professor Gabriel?

Prof. Dr. Gülsah Gabriel in an interview with Der Spiegel on the dangers of influenza.

Interview: Virologist on Pandemic Risk

Prof. Dr. Gülsah Gabriel in an interview with MIT Technology Review on the next candidate pandemic virus.

Leibniz Lab Science Communication Catalogue

A database for collecting scientific content with a focus on sustainability and pandemic prevention.

More Coming Soon

Further news can be found in the News section.